October 2016

August 2016

July 2016

June 2016

May 2016

April 2016

April 2015

March 2016

• Researcher's Toolbox: Sensing Damage
• Dementia: Send in the Clowns
• Neurological Disease: Improving Diagnosis
• Cancer: More Realistic Research Models
• Epilepsy: Targeting Regions of the Brain for Therapy
• Research News: Redefining our Research Enterprise

February 2016

• Kidney Disease: Not a Moment Too Soon
• Stroke: Barriers Preventing Recovery
• Cancer: Sabotaging the Immune System
• Imaging: Detecting Early Signs of Heart Damage
• Arthritis and Bone Health: the Anatomy of Disease
• Immunology: Knowing Yourself Better
• News: Michener Joins the UHN Family
• Funding: Cell Therapy Investment Announced

January 2016

• Cardiac Rehab: Realizing Benefits for Women
• Spinal Injury: Improving Surgical Outcome
• Brain Cancer: Answering an Age-Old Question
• Immune Cells: The Roads that Lead to a Macrophage
• Pancreatic Cancer: New Model to Personalize Treatments
• UHN's 2015 Research Report: E=Health

December 2015: Year in Review

November 2015

• Patient Safety: Identifying Weaknesses in the System
• Cancer: Hospitalization Discrepancy
• Imaging: Pursuit of Sharper Contrast
• Arthritis: Sex Differences Explained
• Alzheimer Disease: Speaking One's Mind
• Kidney Disease: New Biomarkers Predict Severity

October 2015

• Neuroscience: Connectivity Curbs Compulsiveness
• Cardiology: What Makes a Good Heart?
• Researcher Toolbox: Mind over Matter
• Brain Injury: Sad, Sleepless Nights
• Vision Disorders: Connecting the Dots
• Cancer: Radiotherapy Gaps Identified

September 2015

• Preventing Falls: Stepping Up Safety
• Kidney Disease: Predicting who is at Risk
• Arthritis: Link to Vascular Disease Mortality
• Sleep Apnea: Importance of Fluid Buildup
• Surgery: Seeing Tumours more Accurately
• Cancer: New Treatment Strategy

August 2015

• Parkinson: How Deep Brain Stimulation Works
• Rehab: Automated Coach Helps Overcome Disabilities
• Heart Disease: Encouraging Growth Promotes Healing
• Surgery: Negotiating Risk in the Operating Room
• Lung Transplant: Old and Young Benefit Equally
• Researcher's Toolbox: Modelling Bile Duct Disorders
• Funding: Government Supports Stem Cell Research

July 2015

• Alzheimer's Disease: Robots That Give a Helping Hand
• Cancer: Discovery of Genes Driving Prostate Cancer
• Obesity: Better to be Inefficient?
• Genetic Emphysema: Boosting Protein Slows Damage
• Heart Disease: the Path to Targeted Therapies
• Cancer: Understanding Uneven Drug Delivery
• UHN Inventor of the Year Announced

June 2015

• Breast Cancer: Improving Current Treatment Plans
• Infrastructure & Innovation: New Funding from CFI
• Regenerative Medicine: From Stem Cells to Cartilage
• Stroke: The Right Place at the Right Time
• Lung Cancer: When Does Chemotherapy Help
• Genomics: Genome Canada Supports UHN Projects

May 2015

• Diabetes: Therapeutics Activate Gut Nervous System
• Preventing Falls: Get a Grip with Better Footwear
• Obesity: Immune Cells in Gut Impact Blood Sugar
• Pain Management: Seeing How the Brain Responds
• Cancer: Artificial Intelligence and Radiotherapy
• UHN-Developed Medical Technology Products Unveiled
• Northern Biologics Strikes a Deal

April 2015

• Lupus: Blood Molecule a Bad Influence on Immune Cells
• Cancer: New Biomarker for Acute Myeloid Leukemia
• Cancer: Bursting the Microbubble
• Rehab: Targeting Depression and the Fear of Falling
• Schizophrenia: Genes Impact Treatment Response
• Parkinson Disease: A Test for Early Detection

March 2015

• Stroke: Detailed Feedback Speeds up Recovery
• Cancer: Size Matters for Blood Clots
• Transplantation: Identifying the Best Donor Lungs
• Turning Genes On or Off: Bringing Loops into the Fold
• Cancer: Reducing Aggressive Care with Palliative Care
• UHN's 2014 Research Report Wins Top Award

February 2015

• Cancer: Tumours Hijack Antioxidants to Survive
• Physical Activity: Regular Exercise not Enough
• Osteoarthritis: Eating Away at the Joint
• Heart Disease: Harmful Effects of Intense Exercise
• Heart Failure: Inexpensive Test may Save Lives
• HPC4Health Brings Cloud Computing to Health Research

January 2015

• Prostate Cancer: New Genetic Test to Personalize Treatment
• Heart Disease: Promoting Heart Health in Women
• Researcher's Toolbox: Powerful Tool Predicts Protein Interactions
• Dementia: White Matter Matters
• Parkinson Disease: Networks that Control Memory Decline
• Cancer: How Low Oxygen Levels Promote Tumour Growth
• UHN's 2014 Research Report: Medicine Gets Personal

December 2014: Year in Review

November 2014

• Pancreatic Cancer: Blood Proteins Aid in Diagnosis
• Cancer: Examining the Toxicity of New Drugs
• Neuroscience: Regulator of Potassium Channel Function Uncovered
• Transplantation: A Matter of Life and Death
• Psoriatic Arthritis: Improving Early Detection
• Researcher's Toolbox: New Approach Identifies Disease-related Proteins

October 2014

• Stroke: Weekend at Home Contributes to Recovery
• Cancer: Fertile Ground for Growth
• Lupus: New Way to Monitor Symptom Flares
• Prostate Cancer: Accurately Pinpointing Tumours
• Metabolism: Tipping the Balance towards Fat Release
• Funding: Cancer Research and New Stroke Drug

September 2014

• Cancer: A Novel Approach to Decipher Cause
• Chemical Biology: A New Tool to Study the Role of SETD7 Protein
• Sleep Apnea: Passively Measuring Fluid Accumulation with Sound
• Kidney Disease: New Diagnostic Imaging Tools
• Neuroscience: Revealing Regeneration Strategies for the Injured Central Nervous System
• Navigating Canada's Research Facilities

August 2014

• Cancer: Potential AntiCancer Therapeutic Discovered
• Obesity and Depression: Two Sides of the Same Coin?
• HIV: Hormone Linked to Low Birth Weights
• Cancer: Nanoparticles to Visualize and Treat Tumours
• Breast Cancer: Choosing Reconstruction with Surgery
• Motion Sickness: What you Hear Matters

May 2014

• Psoriatic Arthritis: Inflammation that Stiffens Joints and Arteries
• Cancer: A Carrier Particle for Image-Guided Drug Delivery
• Stroke: New Approaches Needed to Help Patients Regain Their Stride
• Parkinson's Disease: Brain Structures Provide Clues to Cognitive Function
• Type 2 Diabetes: Nervous System Key to Prevention
• Facility Spotlight: The Vector Core

April 2014

• Liver Disease: A Breakthrough for Hepatitis C
• Diabetes: Key Regulator of Insulin Secretion Identified
• Autoimmune Disease: Cancer may Trigger Attack on Brain
• Telehealth: Enabling Self-Management of Chronic Disease in Remote Communities
• Biology: Figuring Out How Cells Get Bigger
• Research Facilities Available at UHN

March 2014

• Malaria: Bad Blood and Collateral Damage
• Prostate Cancer: The Cost of Survival in Ontario
• Rehabilitation: Brain Imaging as a Predictor of Physical Fitness
• Cancer: Cost Effectiveness of Personalized Medicine
• UHN Welcomes New Director for Research Commercialization
• UHN's 2013 Research Report Wins Top Award

February 2014

• Vision Disorders: Brain Provides Clues to Protection in the Eye
• Rehabilitation: Support Influences Return Home after Brain Injury
• Radiation Therapy: Modelling Changes in Tumour Geometry
• Leukaemia: Tracing the Earliest Steps of Disease
• Cancer: Earlier Palliative Care Benefits Patients
• Medical Care: Factors that Influence Opioid Use after Major Surgery

January 2014

• Lung Cancer: Smoking Out the Factors That Prevent Quitting
• Diabetes: Leptin in Gut Lowers Blood Sugar
• Cardiac Arrest: Muscle Relaxant Improves Survival
• Spinal Cord Injury: Improving Treatment with Stem Cells and Bioengineering

December 2013: Year in Review

November 2013

• The Grand Opening of the Krembil Discovery Tower
• HIV: A Powerful New Treatment
• Depression: Mapping the Brain to Guide Treatment
• Community Driven Cancer Research Project Begins
• Palliative Care: Specialized Therapy to Help Terminally Ill Cancer Patients Feel Better

October 2013

• Stem Cells: Uncovering Critical Regulator of Blood Cell Development
• Cardiovascular Disease: Curing Hearts with Stem Cells
• Neuroscience: Wandering Away from Pain
• Neuroscience: Making Waves
• Obesity: Reducing Glucose Production in the Liver
• Brain Injury: Staying Active is Key to Recovery

September 2013

• Cancer: The Root Cause of Multiple Myeloma Relapse
• Liver Cirrhosis and Infection: Acute Kidney Injury Predicts 30-day Mortality
• Neurological Disorders: Unarrested Development
• Parkinson's Disease: Impulsive Behaviour and Dopamine
• Cancer: Immune Cell Found to Have Anti-tumour Properties
• Heart Disease: Barriers to Rehabilitation

August 2013

• Cancer: Why Some Treatments May Fail
• Stem Cells: New Role for GATA-3 in Self-renewal
• Diabetes: Pancreatic Islet Cell Balancing Act
• Rehabilitation: Making Powered Wheelchairs Safer
• Medical Imaging: Modeling Blood Flow in Tumours
• Ankylosing Spondylitis: Links with Autoimmunity

July 2013

• Cancer: Developing Better Prognostics for Mantle-Cell Lymphoma
• Stem Cells: Using "Biowires" to Grow Mature Heart Cells
• Neuroscience: Visualizing Emotional Responses during Depression Therapy
• Neurological Disease: Using Stem Cells to Improve Nerve Function
• Cancer: Revealing the Function of the BRCA1 Gene in Breast Cancer
• Osteoarthritis: Studying Recovery Time after Total Joint Replacement Surgery

June 2013

• Stem Cells: Genome-Wide Study of Genes That Regulate Blood Development
• Cancer: Side Effects of Experimental Therapy for Colorectal Cancer
• Vascular Disease: Inflammation Regulation by MicroRNA
• Epilepsy: Brain Signal Variability Predicts Memory Performance
• Stroke: Brains from Brawn

May 2013

• Diabetes: Resistance to Glucagon in the Brain
• Stem Cells: Regulators of Blood Cell Development
• Lung Cancer: Analyzing the Predictive Value of KRAS Mutations
• Biochemistry: Development of the First Viable Experimental Model for Systemic Ceramide Accumulation
• Psoriatic Arthritis: Preventing Joint Damage with TNFa Inhibitors
• Stroke: Swallowing and Speech Impairments After Stroke

April 2013

• Liver Disease: A New Approach in the Treatment of Hepatitis C
• Urology: Prevention of Prostate Disorder Symptoms
• Eye Disease: A New Mechanism that Regulates Cell Death in the Retina
• Parkinson's Disease: Unravelling Crossed Signals
• Lung Transplantation: Preventing Rejection with Gene Therapy
• Rehabilitation: Measuring Balance

March 2013

• Neuroscience: Treating Anorexia with Deep Brain Stimulation
• Cancer: The Causes of Tumours of the Eye
• Cancer: Targeting Hypoxia Tolerance for Improved Cancer Therapy
• Diabetes: Glucagon Response to Fasting and Starvation
• Rehabilitation: Referral Strategies for Women with Heart Disease

February 2013

• Obesity: The Role of Intestinal Bacteria in Fatty Liver Disease
• Leukemia: Stem Cell Transplant Therapy for AML
• Drug Development: New Directions in the Treatment of Multiple Sclerosis
• Arthritis: The Challenge of Integrating Physical Activity into Daily Life
• Stroke: Regaining Balance with Visual Cues

January 2013

• Respiration: Testing a New Model to Treat Lung Injury
• Cancer: New Discovery for Tumour Growth
• Cancer: Refining Treatment of Oropharyngeal Cancer
• Obesity: Protecting the Heart from a High Fat Diet
• Cardiology: Effect of Sleep Apnea on Heart Function
• Genetics: Understanding How Drugs Affect the Entire System

December 2012: Year in Review

November 2012

• Heart Disease: Treating Patients Diagnosed with Diabetes
• Cancer: Palliative Care Referral Practices in Oncology
• Cancer: Novel Imaging and Therapeutic In One Tiny Package
• Bipolar Disorder: Insulin Improves the Mental Performance of Bipolar Patients
• Sleep Apnea: Making Waves in the Link to Renal Disease

October 2012

• Cancer: A Single DNA Nucleotide Difference Regulates Breast Cancer Cell Growth
• Diabetes: The Role of the Brain in Insulin Resistance
• Malaria: Blood Type Influences Disease Severity
• Stroke: An Experimental Model Accurately Predicts the Outcomes of a Therapeutic Stroke Drug
• Genetics: Protein Levels Associated with Behavioural Impairments
• Heart Disease: Timing of Depression on Patient Outcomes

September 2012

• UHN Licenses Cancer Treatment Planning Technology to RaySearch Laboratories
• Cancer: Characterizing the Effect of Genetic Variants in Neuroendocrine Cancers
• Osteoporosis: Inaccurate Assessment of Fracture Risk in Ontario's Non-Urban Areas
• Immunology: Insights into HIV Susceptibility
• SCRIPDB Partners with NIH PubChem

August 2012

• Cancer: Molecular Mechanisms of Cellular Polarity
• Medical Imaging: First Microbubble with Inherent Dual Imaging Properties
• Leukemia: A New Molecular Target for Therapy
• Medical Care: How Surgical Culture Affects Error
• Respiration: New Educational Objectives for Mechanical Ventilation Practice
• Rehabilitation: Measuring Activity with Brain Computer Interface Systems

July 2012

• Leukemia: An Experimental Model for AML Provides New Insights
• Cancer Care: Drug Development and Maintaining Quality of Life
• Rheumatoid Arthritis: Circulating Non-Immune Cells Promote the Spread of Joint Inflammation
• Bipolar Disorder: Making Beneficial Therapy More Accessible
• Exercise: Improving Quality of Life in Patients Undergoing Chemotherapy
• Computational Neuroscience: The Relationship between Individual Neurons and Population Network Activities in the Hippocampus

June 2012

• Colon Cancer: Understanding Self Renewal and Resistance
• Patient Care: A Better Predictor of Heart Failure in Emergency Room Care
• Prostate Cancer: Seeking Out Genetic Variations that Increase Cancer Risk
• Pancreatitis: How Alcohol Damages the Pancreas
• Health Outcomes: Chronic Joint Pain in the Canadian Population
• Influenza: Identifying Risk of Severe Illness

May 2012

• Kidney Failure: Fish Oils May Provide Benefits for Hemodialysis Patients
• Diabetes: Glucose Regulation by the Intestine
• Autoimmunity: Gender Differences in the Immune System
• Hypertension: Managing Blood Pressure with Your Smartphone
• Sleep Apnea: Daytime Alertness may Reveal Heart Health
• Neurology: Exploring the Regulation of Brain Function

April 2012

• Cancer: A New Understanding of Immune System Responses
• Breast Cancer: Gene Signatures for Better Treatments
• Spinal Cord Injury: Reducing Inflammation with a Smart Material
• Diabetes: New Insight into Insulin Release
• Prostate Cancer: Predicting Recurrence using Oxygen Levels
• Stroke Rehabilitation: Determining Fall Prevention Responses in Stroke Patients

March 2012

• Stroke: Development of World's Most Advanced Neuroprotective Drug
• Proteomics: A Novel Method to Identify Stem Cell Types
• Medical Imaging: Novel Tools for Visualizing Tumours Using Nanotechnology
• Metabolism: Appetite Control in the Brain
• Rehabilitation: Psychotherapy Promotes Prolonged Benefits in Patients with Brain Injury
• UHN Licensed Image Guided Irradiator System Reaches 10th Installation Milestone

February 2012

• Structural Biology: Looking Into the Mechanics of Calcium Release
• Development: Imprinting in the Mouse Genome
• Breast Cancer: Risks and Benefits of Prevention
• Neurology: Controlling the Growth of Neurons
• Stroke: Exercise Program for Rehabilitation
• Cancer: Preventing Tumours in Retinoblastoma

January 2012

• Ovarian Cancer: Drug Delays Disease Progression
• Immunity: Regulating the Response to Infection
• Hormone Therapy: Ontario Failing to Treat Osteoporosis-Related Side Effects
• Metabolism: How the Gut Controls Glucose Production
• Immunology: A New Model for Injury Repair in the Eye
• Social Media: The Role of Twitter in Assessing Scientific Impact

December 2011: Year in Review

November 2011

• UHN and University of Toronto Launch Techna Institute
• iDAPT: World Class Innovation at Toronto Rehab
• Prostate Cancer: Combination Treatment Greatly Improves Survival
• Cardiology: Sodium Intake Increases Risk of Sleep Apnea
• UHN Educational Tool Licensed to Edwards Lifesciences
• Inflammatory Arthritis: Identifying Risk of Disease Progression

October 2011

• PMH Awarded Third National Cancer Institute Contract
• Immune Disorders: New Insights into Cell Regulation
• Immunity: Cell Adhesion in Leukocytes
• Neurology: Uncovering Factors Associated with the Development of Neurons
• Clinical Trials: The Impact of Announcements on Company Stock Prices
• Alzheimer's Disease: Quality of Life Assessed by Family Caregivers

September 2011

• UHN Medical Imaging Tool Licensed to Vexim SA
• Cancer: Creating a Blueprint of Protein Modifications
• Cardiology: Distinguishing the Mechanisms of Heart Contraction
• Psoriatic Arthritis: The Disease within a Disease
• Pulmonary Disease: Increasing Physical Activity
• Nanomedicine: Delivery of Anticancer Drugs
• Cardiology: Reducing Inflammation in Damaged Cardiac Muscle
• Stroke Prevention: Assessing the Effects of Surgical Revascularization

August 2011

• Strategic Planning Needs Your Help
• Autoimmune Diseases: Explaining the Role of PTPN22 in Immunity
• Leukemia: Stem Cell Properties Correlate with Disease Outcome
• Immunity: Identifying the Mechanisms Involved in Inflammation of the Colon
• Spondyloarthritis: Impact on Social Life
• Radioisotope Therapy: The Future of Antibody Linked Radiotherapy
• Osteoporosis: Better Prevention from Future Injury

July 2011

• UHN's New Office of Research Trainees
• Stem Cells: Isolation of the Purest Blood Stem Cells
• Clinical Trials: Assessing the Effects of Unpublished Data
• Gastroenterology: New Insights into Blood Glucose Regulation
• Blood: New Directions for Disease Treatment
• Stroke: Understanding the Short-Term Outcomes for Artery Blockage

June 2011

• UHN and Toronto Rehabilitation Institute Announce Their Integration
• Neurology: Stimulation of the Motor Cortex Improves Hand Tremors
• Leukemia: New Cancer Stem Cell Factor Identified
• Cardiology: New Role for Protein in Heart Function
• Myeloma: Antitumour Activity with New Therapeutic Drug
• Stem Cells: Characterizing Neural Stem Cell Development

May 2011

• Health Services Research at UHN: Strategic Planning Workshop
• Prostate Cancer: New Findings on the Effects of Supplements
• Cancer: A New Mechanism for Resistance to Therapy
• Leukemia: Helping the Immune System Fight Cancer
• Parkinson's Disease: Enhancing the Therapeutic Benefits of L-DOPA
• Neuroscience: Understanding the Effect of Seizures in Stroke Patients
• Acute Lung Injury: New Insight into Factors Involved in Cell and Tissue Damage

April 2011

• Lung Transplantation: High-Risk Donor Lungs Can Now Be Safely Used for Transplant
• Respiratory Disease: Long-Term Study on the Effects of Acute Illness
• Lung Cancer: Changes in Non-Cancer Cells May Predict Patient Outcome
• Diabetes: New Guidelines for Treating Diabetic Neuropathy
• Neurology: Surgical Procedure Reverses Loss of Brain Matter
• Autoimmune Disease: New Suppressor Gene Discovered in Lupus-Prone Mice

March 2011

• Cancer: Novel Organic Nanoparticles for Cancer Targeting and Treatment
• Cardiology: Novel Peptide Helps to Prevent Damage Following Cardiovascular Injury
• Pancreatic Cancer: Hypoxia Predicts Growth and Metastasis
• Stroke: Why Sleeping Better is Good for Stroke Patients
• Intracerebral Hemorrhage: Identifying a Culprit in Brain Injury
• Arthritis: Examining Workplace Activity Limitations

February 2011

• Leukemia: Uncovering Genetic Diversity in Propagating Cells
• HIV Infection:  Promoting the Immune Response to Chronic Viral Infections
• Regenerative Medicine: Development of Heart Cells from Stem Cells
• Depression: Deep Brain Stimulation Shows Benefit in 3 and 6 Year Follow-Up Study
• Parkinson Disease: New Insights into the Role of the Cerebellum in Disease Development
• Heart Disease: A Novel Mechanism of Electrical Remodeling in Cardiac Hypertrophy and Heart Failure

December 2010: Year in Review

October 2010

• Cancer: Identifying the Cells that Cause Cancer
• Lung Cancer: Gene Signature Helps Predict Benefits of Chemotherapy
• Neuroscience: The Cellular Basis of Neural Impulse Transmission
• Heart Disease: Preventing Injury Following Transplantation
• Diabetes: Detecting Sugar Sensing Pathways in the Brain
• Virology: Developing New Methods to Fight off SARS
• Parkinson's Disease: Learning the Benefits of Combined Therapy

September 2010

• Primary Biliary Cirrhosis: Confirming Gene Involvement
• Leukemia: Timing DNA Repair and Cell Death to Prevent Cancer
• Alzheimer's Disease: Investigating New Stimulating Treatment Techniques
• Neurology: Understanding How Perception of Pain Affects Recovery

July 2010

• Influenza A: Identifying New Cell Populations to Battle Disease
• Immunity and Disease: Applying Cell Therapy to Combat Infectious Disease
• Hodgkin Lymphoma: Investigating Heart Disease Risk and Cancer Treatment
• Lupus: Monitoring Heart Disease Risk in Patients
• Parkinson's Disease: Understanding the Anatomy of Movement

June 2010

• ELLICSR Opens its Doors
• Immune System: Revising the 'Road Map' of Blood Development
• Malignant Mesothelioma: Identifying New Investigative Tools
• Cancer: Depression in Patients with Advanced Disease
• Neurology: Targeting Brain Communication Circuits to Understand Disease

May 2010

• UHN Captures $30M in New Ministry Funding
• Breast Cancer: Hormone-Driven Cell Growth
• Irritable Bowel Syndrome: Brain Landscape Changes and Disrupted Communication
• Neurology: Determining When to Re-Start Anticoagulation
• Diabetes: Locating the Brain's 'Sweet Spot'

April 2010

• Structural biology: Understanding How Cells Anchor
• Malaria: How Maternal Infection Contributes to Low Birth Weight
• Lymphoma: Opening the Door to New Research and Treatments
• Lung Cancer: Economic Analysis of Targeted Therapy
• Parkinson's Disease: Learning the Long-Term Effects of Deep Brain Stimulation

March 2010

• Lupus: Investigating Antimalarial Treatments
• Head and Neck Cancer: Using Global Screens for New Target Identification
• Lung Injury: Getting to the Bottom of Injury Promotion and Prevention
• Neurology: Establishing a Circulation and Brain Landscape Relationship

February 2010

• Leukemia: Elucidating Genetic Areas of Control
• Heart Failure: Tracking Patients after Discharge
• Cancer: Understanding Timing and Tumor Development
• Liver Transplant: Determining When and Why to Apply the Surgical Brakes
• Regenerative Medicine: Repairing the Injured Spinal Cord
• Rett Syndrome: Surveying Brain Patterns to Increase Disease Knowledge

January 2010

• Cancer: Changing Current Understanding of Gene Function
• Leukemia: New Population of Cells Discovered
• Cancer Biology: Sensitizing 'Tenacious' Tumour Cells
• Neurology: Detailing the Memory Process
• Cardiology: Re-Examining Protective Properties of Beta-Blockers

December 2009: Year in Review

November 2009

• Lung Transplantation: Gene Therapy Repairs Injured Lungs
• Head & Neck Cancer: Clarifying Trial Terminology
• Parkinson's Disease: 'Stimulating' Ways to Prevent Falls
• Diabetes: Focusing on Early Diabetes Complications
• Brain Injury: Understanding Factors Contributing to Damage
• Breast Cancer: Understanding the Relationship between Treatment and Menopause

October 2009

• Atherosclerosis: Outlining Disease Beginnings
• Cardiology: Understanding the Benefits of Salt
• Stroke: Suppressing Brain Cell Death
• Neurology: Mapping Nerve Changes
• Oral Cancer: Identifying New Biomarkers of Disease
• Nasopharyngeal Cancer: Elucidating Disease Proteins

September 2009

• Lung Cancer: Enhancing the Decision-Making Process
• Diabetes: New Protein Discovery
• Neurology: Changing Current Beliefs
• Cancer: Identifying New Potential Drug Use
• Malaria: Defining Future Treatment Options
• Neurology: Preventing Ocular Cell Death

July 2009

• New CFI Funding Announced
• AL-amyloidosis: Discovering Treatment Strategies
• Cardiovascular Disease: Treatment Implications
• Regenerative Medicine: Defining Growth Requirements
• Parkinson's Disease: Mapping the Effects of Stimulation

June 2009

• Primary Biliary Cirrhosis: Grabbing Hold of Genetics
• Ovarian Cancer: Patupilone Phase I Safety Findings
• Arthritis: Taking a Closer Look at Gender
• Lung Transplantation: Dealing with Rejection
• Esophageal Cancer: Identifying Markers of Disease

May 2009

• Cancer: Boosting the Body's Immune System
• Breast Cancer: Assessing Risk Early-On
• Malaria: Pregnancy and Treatment
• Noonan Syndrome: Discovering the Mechanics of Disease
• ADHD: Genetics of Disease
• Kidney Disease: Identifying Growth Pathways

April 2009

• Malaria: Biomarker Discovery
• Liver Cancer: Novel Treatment Strategy
• Parkinson's Disease: Deciphering Cell Communication
• Neurology: Imaging the Brain
• Breast Cancer: Revisiting Treatment Strategies

March 2009

• Cancer: Using Algorithms to Detect Gene Patterns
• Lung Cancer: Three-Sided Approach to Treatment
• Neurology: Exploring the Use of New Research Tool
• Major Depressive Disorder: Profiling Treatment
• HIV: Evaluating New Therapy Options

February 2009

• Cancer: New Technology to Study Structure
• Regenerative Medicine: Novel Findings for Lung Repair
• Cardiology: Avoiding Acute Kidney Injury
• Cancer: The Genetics Behind Chronic Myeloid Leukemia
• Ankylosing Spondilitis: Discovering Biomarkers of Disease

January 2009

• Cancer: Illustrating Form and Function
• Cancer: Outpatient Palliative Care Interventions
• Parkinson's Disease: Investigating Brain Cell Connections
• Lupus: Monitoring the Advantages of Methotrexate
• Thyroid Cancer: Revealing Where Growth Starts
• Virology: The Mechanisms of Infection

December 2008: Year in Review - UHN Research in 2008

November 2008

• Directing Heart Cell Development
• 'Checking' Immune Cell Balance
• Remodeling the Heart After Injury
• Surprising New Model for Cancer Cell Aging
• Psoriatic Arthritis Researchers Tackle Fatigue
• Weight Management Prediction in Anorexia

October 2008

• Signal Control in Immunity
• Thyroid Cancer Cells 'Staying Put'
• 'Current' Neural Regenerative Medicine
• Injury Mechanics in Neurology

September 2008

• Landmark $120M Funding to UHN
• Cancer Protein and Male Infertility
• Forecasting Hepatitis with Disease Marker
• 'Report'ing on the Immune System
• Indicators of Lung Cancer Therapy Response
• Eating Behaviors in Diabetic Teen Girls

July 2008

• Enzyme Deficiency in Malaria
• Genetic Changes Involved in Colorectal Cancer
• A New Therapeutic Approach for Hepatitis B
• Family Involvement in Psoriatic Arthritis
• How Hospital and Surgeon Volume Affects Prostate Cancer
• Movement Control Tactics in Parkinson's Disease

June 2008

• Tuning the 'Engine' of Immune Response
• The Role of Fat in Diabetes and Cardiology
• Innovative Cancer Treatment Moves to Phase II
• Defining Mechanisms of Brain Degeneration

May 2008

• Regenerative Medicine and Cardiac Cells
• Three-Way Communication in Diabetes
• Controlling the Host Response in Malaria
• Arthritis Medication Raises Caution
• New Potential for Parkinson's Disease
• Understanding Growth in Pituitary Cancer
• Lung Cancer and Immune Cells
• New Predictors in Prostate Cancer

April 2008

• Hypertrophy and Cardiac Cells
• Nomograms for Phase II Clinical Trials
• Stroke and the Penumbra
• Decision Aids for Cancer Patients

March 2008

• Smooth Muscle Cells in Cardiology
• Revisiting Survival in Prostate Cancer
• Alzheimer's Disease and DBS
• Gene Targeting in Rett Syndrome
• Retinoblastoma and Genomic Instability
• Disease Management in Lupus
• Couples Intervention for Cancer

January 2008

• New Tool for Stem Cells
• 3D Liver Cancer
• Lupus Development
• Profiling Cerebral Malaria
• IBS and Pain
• Treating Type II Diabetes

Special Holiday Issue: 2007 Research Breakthroughs

November 2007

• Optimizing Treatment Decisions in Bladder Cancer
• Childhood Mood Disorders
• Myeloma: Drug Screen Points to New Therapy
• Learning to Control Cancer Growth and Survival Genes
• Motivations Behind Genetic Testing in Colorectal Cancer

October 2007

• Building Blocks of Cancer Cells
• Controlling Lung Cancer Growth
• How Age can Affect Cardiac Patients
• Understanding the Mechanics of Memory
• Type 1 Diabetes and the Immune System: The Link
• Using Stem Cells for Respiratory Diseases
• Factors Promoting Osteoporosis

June 2007

• ALS and Protein Folding
• Brain Tumour Suppressor Gene
• Cancer Survivors and Cognitive Impairment
• Pancreatic Cancer Treatment
• Cardiovascular Disease and Vitamin C
• Proteins and the Immune Response
• Glucose Metabolism and Brain Activity
• Neural Remodeling

May 2007

• Mapping Human Leukemia in Mice
• Influenza A Transmission
• 'Check'ing Out Cancer
• Rebuilding Myelin in Spinal Cord Injury
• Personalizing Cancer Treatment
• Live Donor Transplants Cut Waiting Times
• Drug Interactions in Cancer
• Premier's Summit Awards
• CFI Awards

April 2007

March 2007

February 2007

January 2007

• • Discovering the Cancer "On Ramp"
  • Understanding Cardiac Repair
  • Screening Hodgkin's Lymphoma Survivors
  • New Cancer Drug Target
  • Paying Attention to Genetics in ADHD
  • The Importance of Day/Night Schedules
  • Nerve Architecture
  • Sleep Apnea Featured
  • A Deeper Look into Movement Disorders
  • Protein Balance in Cancer
  • Focusing on Fatigue
  • Engineering Lung Tissue
  • Controlling Arthritis Activity
  • New Informatics Editor-in-Chief
  • Unraveling Statins
  • Microglia in Brain Trauma and Stroke
  • Cell Communication in the Brain
  • Arresting Tumour Growth
  • Alzheimer's Gene Found
  • Examining Breast Tissue Density and Risk
  • Controlling Fat Levels in Diabetes and Obesity
  • Swallowing Disorder Treatments Assessed
  • Multi-pronged Approach for Treating Brain Injuries
  • Notochord Cells Protect Spinal Discs
  • Thyroid Cancer Metastasis Marker Proposed
  • New SARS Animal Model Tested
  • Potential Improvements for Hepatitis C Treatment

Special Holiday Issue: 2006 Research Breakthroughs

Special Issue: Research Day 2006

• • Dr. Peggy Farnham 'ChIP'ping Away at Tumour Identity
  • Dr. Lozano Inventor of the Year
  • Trainees of the Year: Bill Ayach, Peter Stogios, and Dr. Cindy Zadikoff
  • Accolades for Presentation Winners
  • Thanks to the Research Day Team
  • Research Breakthrough: Colon Cancer Rooted in Stem Cells

November 2006

• Bone Pain Reduced
• Testing the Fates of Stem Cells
• Drug Improves Quality of Life in Lung Cancer
• Importance of Arthritis Education Reinforced
• New Potential Anti-cancer Agent Found
• Genetic Disorders: "Record" Result

October 2006

Special Issue: Regenerative Medicine

• Antibody Attacks AML
• Spinal Cord Injury Stemmed
• Fabry Symptoms Foiled
• Anti-Rejection Drug Defined
• C-kit Sounds Siren
• Gene Set Match for Lesioned Livers

September 2006

• Dendritic Cells Dominate
• Repair "Troops" Signalled after Heart Attack
• 3D Structure of Leukemia Molecule Limned
• (OD)Case Study: Novel Inhibitors

June 2006

• ARDS: Study Shows Long-Term Outcomes for Survivors
• Blood Vessel Disorders: Molecules Offer New Therapy Target
• Anorexia Nervosa: Study Suggests Need to Reconsider Treatment
• Cancer: Anti-Aging Molecule May Help in Cancer Fight
• Brain Surgery: New Model Predicts Outcomes

May 2006

• Transplantation: New Test Will Increase Pool of Donor Lungs
• Alzheimer's Disease: Finding Offers New Therapeutic Targets
• Cancer: New UHN Software Finds Partner "Suspects"
• Better Liver Transplants: Answer's in the Genes

April 2006

• Balancing Hope & Knowledge in Cancer Decision-Making
• Molecule Helps Body Clean Up
• Electrode Brain Treatment Reduces Seizure Number

March 2006

• Gene Bars Rod Development
• Drug Pressures Tumours
• New Direction for Repairing Blood Vessels

February 2006

• Aching to Sleep
• Imaging Inner Geometry
• Knowledge of Immune Molecule Growing
• Enzymes at the Heart of Structural Changes
• New Repair [c-]Kit for Heart Disease
• Infection Target Iron-ically Obvious

January 2006

• ADHD Genetic Risk Factor
• DNA Break-ing News
• Missing Molecule Stops Signals
• New Role for MyD-88
• Defect Found in Lupus-like Syndrome

November 2005

• Achievements Displayed at Research Day
• Dr. Michael Sefton Talks Regenerative Medicine
• 2005 Inventor of the Year: Dr. Joseph Fisher
• UHN Research Applauds Abstract & Poster Winners
• Thanks to the Research Day Team test

October 2005

• Telomerases Behaving Badly
• Behind the (Caspase-)Eight Ball
• Molecule Required for Immune Cell Survival
• Molecule First in Line
• OCD-Related Neurons Pinpointed

September 2005

• Molecule Mediates Metastasis
• Stopping Sleep Symptom Silences Sympathetic Signals
• Motor Memories: Total Recall

Summer 2005

• Drug prolongs lung cancer survival (OCI/PMH)
• Reducing rejection in transplant (TGHRI/TGH)
• Killer molecule identified (Krembil/TWH)
• Dynamic duo in heart disease (OCI/PMH and TGHRI/TGH)

June 2005

• Age a Factor in Treatment Decisions (OCI/PMH)
• New Tools in Pancreatic Cancer Research (OCI/PMH)
• Understanding Xenograft Rejection (TGHRI/TGH)
• Deep Brain Stimulation Effect Indirect (Krembil/TWH)

May 2005

• Genes predicting hep C treatment response identified (TGHRI/TGH, OCI/PMH, Krembil/TWHI)
• Gene provides protection against Parkinson disease (Krembil/TWH and AMDI/OCI/PMH)
• First link between immune and hormonal systems pinpointed at UHN (OCI/PMH)
• Diabetes finding may lead to new preventive and treatment measures (OCI/PMH and Krembil/TWH)

April 2005

• Special Issue: New Division Heads Appointed at OCI

March 2005

• Fruit Flies and Cancer Research (AMDI/OCI/PMH and OCI/PMH)
• New Treatment for Depression (Krembil/TWH)
• Personalized Cancer Therapy (TGHRI/TGH)

February 2005

• Women Respond Better to Lung Cancer Treatment (OCI/PMH)
• Binge/Purge Behaviours Reduce Anorexia Treatment Success (TGHRI/TGH)
• Phantom Sensations Probed (Krembil/TWH)

January 2005

• Finding Will Lead to Targeted Therapies for Heart Disease and Brain Disorders(OCI/PMH)
• Risk Factor for Dyslexia Identified (Krembil/TWH)
• DNA Repair in Prostate Cancer: When Too Much Isn't Enough (OCI/PMH)
• Study Zeroes in on Predictors of Parkinson Disease Survival (Krembil/TWH)
• Molecule Critical for Fighting Viral-Induced Heart Disease (TGHRI/TGH)
• Exercise Eases Symptoms of Musculoskeletal Disease (TGHRI/TGH)

December 2004

• • Defect a Cause of Parkinson Disease (Krembil/TWH)
  • Successful Treatment for Fabry Disease (OCI/PMH)
  • Anxiety Bad for Heart Patients (TGHRI/TGH)
  • Finding Important for Heart Disease (OCI/PMH)

November 2004

• • New Treatment for Prostate Cancer (OCI/PMH)
  • Clues to Cause of Autoimmune Disease Uncovered (AMDI/OCI/PMH)
  • A Busy Brain May Overlook Pain (Krembil/TWH)
  • Protein Critical for Genome (OCI/PMH)
  • Clues for Treating Rare Cancer Revealed (TGHRI/TGH)
  • Group Therapy Eases Cancer Fears (TGHRI/TGH)

October 2004

• • Update: Strategic Planning in Research at UHN

September 2004

• • Combined Therapy Benefits Breast Cancer (OCI/PMH)
  • Flick the Switch on Disease (OCI/PMH)
  • New Treatment for Huntington's Disease (Krembil/TWH)
  • Regulation of Appetite is Complex (TGHRI/TGH)
  • Molecule Protects Infection Fighting Cells (AMDI/OCI/PMH)

Summer 2004

• • Protein a Cancer Alert (OCI/PMH)
  • Molecular Complexes Control Brain Function (Krembil/TWH)
  • Heavy Hearts Lifted (TGHRI/TGH) Damaged Clock Proteins
  • OCI/PMH) Stroke Culprit Fingered (Krembil/TWH)
  • Heart Disease Risk Factor Identified (TGHRI/TGH)
  • Chromosome Tips and Cancer (AMDI/OCI/PMH)
  • The Kidney's Role in Heart Failure (TGHRI/TGH)

June 2004

• • Faulty Genes in Breast Cancer (OCI/PMH)
  • Clue to Child Cancer Found (Krembil/TWH)
  • "Hidden" Cells in Leukemia (TGHRI/TGH)
  • Target for Autoimmune Disease Identified (TGHRI/TGH)
  • Gene Therapy and Hodgkin's Disease (OCI/PMH and TGHRI/TGH)
  • Secrets of Body Clock Revealed (Krembil/TWH)

April 2004

• • Crohn's Disease Gene Found
  • New Target for Spinal Cord Injury Identified
  • PTEN Implicated in Prostate Cancer
  • Gene Expression—a "Change of Heart"

March 2004

• • New Hope for Neurological Diseases
  • Immune Cells Can Cause Heart Failure
  • Defective B Cells May Hold Key to Lupus
  • Protein a Possible Target for Cancer Therapy

February 2004 The Continuum of Research at UHN

• • Biomedical Research Types: The Overview
  • Basic Research : Examples
  • Translational Research : Examples
  • Clinical Research : Examples

• January 2004
   
  • Brain Damage Culprit Fingered
  • Measuring Dosage: Photodynamic Therapy
  • New Tool for Understanding Brain Chemistry

December 2003

• • Long-term Effects of Chemotherapy Studied
  • Protein Fuels Autoimmunity
  • Model Helps Choose Best Care for Heart Disease

November 2003 Clinical Trials at UHN (Part II of II)

• • Finding the Best Treatment for Heart Failure
  • Patients Use Tools to Understand Cancer
  • Treating Psychotic Depression
  • Attacking the Cause of Lung Disease
  • Testing a New Rapid Treatment for Prostate Cancer
  • Imaging Parkinson's Disease
  • Novel Therapy for Ankylosing Spondylitis

October 2003 Clinical Trials at UHN (Part I of II)

• • Promising New Breast Cancer Drug Validated
  • Drug Acts as "Trojan Horse"
  • Patients Can Enjoy Comforts of Home
  • New Treatment for Malaria
  • Vitamin K and Osteoporosis

September 2003

• • New Treatment Strikes at SARS
  • A Healthy Body Weight is Key to Treatment Success
  • Too Much Iron Can be Bad for Your Heart
  • New Role for an Old Molecule

Summer 2003

• • New SARS Test Tested
  • Personalized Care for Colon Cancer
  • Molecule Critical for Immune Function
  • Protein Involved in Brain Development

June 2003

• • Development of a "Genetic Smart Bomb"
  • New Clues for Treating Immune Disorders
  • Keeping HIV out of Cells

May 2003 Update on UHN Research Strategic Planning

• • Platform Executives Announced

April 2003 Celebrating Creativity and Innovation in Research

• • Vitamin A and Malaria
  • Shedding Light on Breast Cancer Risk
  • Viruses for Benefit
  • Entrepreneurs in Research

March 2003

• • Gene Therapy and Hepatitis C
  • SARS-Related Lung Disease
  • Ankylosing Spondylitis

February 2003

• • Healing the Heart with Bone Cells
  • Arthritis in La Belle Province
  • Membrane Proteins

January 2003

• • Cancer Genes and the Genome
  • New Hope for Transplant Recipients
  • Parkinson's Disease