The vision of our research program is multifaceted. The ultimate goal of our research is to enhance the care of patients with genetic-based arrhythmia disorders through clinical and precision medicine research approaches and to establish potential novel drug targets for therapeutic targeting. Our research aims are as follows:
- Identify novel genetic contributors of arrhythmia syndromes, including atrial fibrillation, sudden death arrhythmias and brady-arrhythmias
- Describe novel cellular physiological mechanisms contributing to arrhythmia syndromes
- Develop experimental models of arrhythmia syndromes to delineate in vivo physiology and/or test novel drug therapies
- Participate in international collaborative studies and clinical descriptive studies of arrhythmia cohorts
- Translate genetic discoveries to elucidate the physiological mechanisms of abnormal cardiac rhythms in humans
- Apply genetic information in the care of patients with inherited heart rhythm disorders