0000-0002-3634-6463My lab takes an integrated approach to studying the links between stress, synaptic plasticity, neural circuits and behaviour. We use cell-targeted, circuit-based tools to examine specific nodes that link stress and distinct behaviours. We have uncovered new biochemical pathways that prime synapses and encode mechanisms of plasticity in response to stress; we have described previously unknown roles for canonical neuroendocrine cells in regulating stress behaviour; we have provided new insights into how stress can be transmitted from one individual to another. We are now poised to use this information to develop interventions that can mitigate or erase the effects of stress. This includes the development of stimulation protocols in combination with specific targeting of biochemical pathways, and distinct behavioural manipulations in specific time windows after stress to reverse the synaptic and circuit changes imposed by stress.