Bryan Coburn, MD, PhD, FRCPC

Senior Scientist, Toronto General Hospital Research Institute (TGHRI)
Keywords: microbiome, microbial genomics, infection, chronic respiratory disease, infectious diseases, clinical trials, human microbiome

I am a Clinician-Scientist in Infectious Diseases (ID) at the University Health Network in Toronto, where I attend on the inpatient General ID consult service (at Toronto General, Toronto Western, and Mount Sinai Hospitals) and have outpatient practices in post-discharge General ID follow-up, HIV treatment and prevention, and Tuberculosis (at the TWH TB clinic). I lead an Infectious Diseases Clinical Research Unit at the UHN that undertakes human clinical trials in infectious diseases, antimicrobial stewardship, and microbiome-targeting therapies.

My lab studies human microbiomes in health and disease, including human clinical trials of microbiome-targeting therapies in infectious and non-infectious diseases. We are specifically interested in the effects of various treatments (particularly antibiotics) on the composition of the gut microbiome and microbiomes of other mucosal surfaces. Our goal is to translate our understanding of the complexity and function of the human microbiome to diagnosis, prognosis, and treatment of human diseases in which microbiome perturbation has been implicated, including sexual/reproductive health, cancer, critical illness, and the treatment and prevention of bacterial infections.

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For a list of Dr. Coburn's publications, please visit PubMed or Scopus.

Senior Scientist, Toronto General Hospital Research Institute (TGHRI)

Assistant Professor, Department of Laboratory Medicine & Pathobiology, University of Toronto
Associate Professor, Department of Medicine, University of Toronto