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Alterations in metabolism are a key indicator of cancer. My research is focused on identifying potential metabolic markers of disease using high-field Nuclear Magnetic Resonance (NMR) spectroscopy and the development of clinical applications of MR-spectroscopic imaging (MRS/I). Clinically, MRS/I provides a non-invasive means of studying biochemical processes intrinsic to tumor development and response to treatment at an earlier stage than is possible using anatomical MRI. MRS/I may also provide prognostic information to select appropriate treatment; a means with which to evaluate tumor sensitivity and resistance to therapy; and ultimately, a better understanding of the biological mechanisms underlying cancer onset and progression.